REGEMAT 3D Technology Powers Breakthrough in Bone Regeneration withMultimaterial Synthetic Grafts

Granada, Spain – December 11, 2024 – REGEMAT 3D congratulates the research team
from the University of Iowa on their recent publication describing the development of
multimaterial synthetic bone grafts designed to enhance bone defect regeneration
through the sustained delivery of miR-200c.
The study features the fabrication of gelatin-coated, 3D-printed polycaprolactone (PCL)
scaffolds, created using a REGEMAT 3D bioprinter, showcasing the role of precise
bioprinting in building clinically relevant solutions. By adjusting gelatin types, coating
concentrations, and crosslinking agents, the researchers optimized the release of pDNA
encoding miR-200c, significantly boosting osteogenic activity in vivo.
This innovative work demonstrates the potential of combining bioprinting, gene delivery,
and advanced biomaterials to accelerate bone regeneration and advance tissue
engineering therapies.
We extend our congratulations to the authors — Matthew Remy, PhD, Chawin Upara,
Qiong Ding, Jacob Miszuk, Hongli Sun, and Liu Hong — for their significant contribution
to regenerative medicine.

Read the full publication: https://lnkd.in/dVS-tjsU
To learn more about how REGEMAT 3D supports research breakthroughs, visit
www.regemat3d.com

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