BMAP Knee Bioreactor
Bmap KNEE is the only commercial bioreactor in the world designed specifically for maturing knee cartilage tissue. This patented bioreactor replicates the human knee’s physiological conditions with unique precision, providing advanced mechanical stimulation and a fully controlled, bioactive environment for tissue maturation. Researchers and industry professionals can rely on BMAP Knee to bridge the gap between 3D bioprinting and functional tissue engineering, ensuring that lab-grown cartilage becomes robust, clinically relevant grafts.The Bmap KNEE bioreactor accommodates a real anatomical joint model – combining bone and cartilage components – and applies controlled movements (traction-compression, flexion-extension, rotation, etc.) that mimic the human knee’s natural motions Inside a sterile chamber with tightly regulated temperature, CO₂, pH, chondrocyte-laden constructs undergo conditioning 24/7, “training” the tissue as if it were in vivo. After weeks of bioreactor conditioning, the result is functional cartilage tissue that can potentially be implanted to repair knee defects.
Description
– Technology: Patented bioreactor for osteochondral tissue maturation.
– Environmental Control: CO₂ (%), temperature, pH, and mechanical loading (Kg).
– Movement Simulation: Compression, flexion-extension, rotation, lateral displacement.
– Sterile Biocapsule: Houses patient-specific knee joint models (CT/MRI-based).
– Sensors: CO₂, temperature, and pH monitoring.
– Biomechanical Conditioning: Enhances ECM synthesis and chondrogenic differentiation.
– Software: Real-time monitoring, motion control, automated data logging.
– Applications: Cartilage regeneration, osteoarthritis modeling, implant preconditioning.
– Validation: Functionally and biologically tested for cartilage tissue engineering.